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CS-W001157 4
Total: USD 88.00

2-Nitrobenzene-1,4-diamine

  • CAS No. 5307-14-2

  • Cat. No. CS-W018077
  • Purity≥96%
  • MDL No.MFCD00007903

*For research and further manufacturing use only, not for direct human use.

2-Nitrobenzene-1,4-diamine|CS-W018077

Structure of 5307-14-2

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General Information

  • CAS No. 5307-14-2
  • Cat. No. CS-W018077
  • Purity ≥96%
  • MDL No. MFCD00007903
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₇N₃O₂
  • Molecular Weight 153.14
  • Synonym(s) None
  • SMILES NC1=CC=C(N)C=C1[N+]([O-])=O

Application

2-Nitrobenzene-1,4-diamine serves as a key building block for heterocyclic scaffolds and functionalized aromatic systems. Its dual amine and nitro functionalities enable sequential transformations in medicinal chemistry and materials science, including reductive amination, diazotization, and coupling reactions. The compound exhibits good bench stability and facilitates efficient purification, making it well-suited for scalable synthesis and process development workflows.

Synthesis

  • Route1
    • null|null
      97-02-9
    • ~3%
    • In-stock
      2-Nitrobenzene-1,4-diamine|CS-W018077
      5307-14-2
    • null|null
      99-56-9

    References

    • Bulletin of the Chemical Society of Japan, , vol. 56, # 10 p. 3159 - 3164
  • Route2
    • null|null
      97-02-9
    • ~46%
    • In-stock
      2-Nitrobenzene-1,4-diamine|CS-W018077
      5307-14-2

    References

    • Lazer, Edward S.; Anderson, James S.; Kijek, James E.; Brown, Keith C. Synthetic Communications, 1982 , vol. 12, # 9 p. 691 - 694
  • Route3

    References

    • Forlani, Luciano; Boga, Carla; Mazza, Milena; Cavrini, Vanni; Andrisano, Vincenza Tetrahedron, 1998 , vol. 54, # 18 p. 4647 - 4654

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H317-H401
Precautionary Statements : P261-P272-P273-P280-P302+P352-P362+P364-P501

Quality Control

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Computational Chemistry Data

  • TPSA   95.18
  • LogP   0.7592
  • H_Acceptors   4
  • H_Donors   2
  • Rotatable_Bonds   1

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