2-Bromo-4-methylthiophene

Name: 2-Bromo-4-methylthiophene
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 53119-60-1
Cat. No. CS-0022356
Purity≥95%
MDL No.MFCD12033287

HazMat Fee +

HazMat Fee

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

The shipment is processed through FedEx Ground under the Limited Quantity option.

Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

Structure of 53119-60-1

Size

Price

Quantity

* Please select Quantity before adding items.

General Information

CAS No. 53119-60-1
Cat. No. CS-0022356
Purity ≥95%
MDL No. MFCD12033287
Storage 4°C
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₅H₅BrS
Molecular Weight 177.06
Synonym(s) 5-Bromo-3-methylthiophene; 4-methyl-2-bromothiophen
SMILES CC1=CSC(Br)=C1

Description

2-Bromo-4-methylthiophene is a bench-stable, electron-deficient heterocycle featuring a bromine substituent at the 2-position and a methylthio group at the 4-position. This combination enables direct functionalization in cross-coupling reactions, offering efficient access to substituted thiophene architectures. The molecule's defined regiochemistry supports predictable reactivity in synthetic transformations.

Application

2-Bromo-4-methylthiophene serves as a versatile building block in synthetic organic chemistry, enabling palladium-catalyzed cross-coupling reactions such as Suzuki, Stille, and Negishi couplings. The bromine substituent provides high reactivity under standard conditions, while the methylthio group offers moderate stability and orthogonal functionality for further derivatization. Its bench-stable nature and compatibility with diverse reaction environments make it a practical choice for constructing substituted thiophene scaffolds in medicinal chemistry and materials science applications.

Synthesis

Route1
- 616-44-4
- ~%
- In-stock
  
  53119-60-1
References
- Consiglio, Giovanni; Spinelli, Domenico; Gronowitz, Salo; Hoernfeldt, Anna-Britta; Maltesson, Britta; Noto, Renato Journal of the Chemical Society, Perkin Transactions 2: Physical Organic Chemistry (1972-1999), 1982 , p. 625 - 630

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS02
Signal Word : Danger	UN#: 1993
Class : 3	Packing Group : Ⅲ
Hazard Statements : H225
Precautionary Statements : P210-P233-P240-P241-P242-P243-P280-P370+P378-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

TPSA 0
LogP 2.81902
H_Acceptors 1
H_Donors 0
Rotatable_Bonds 0

Other Classifications

Building Blocks Skeleton Aromatic heterocycle compounds Thiophene compounds

Key Words

2-Bromo-4-methylthiophene sigma2-Bromo-4-methylthiophene manufacturer2-Bromo-4-methylthiophene price2-Bromo-4-methylthiophene structure2-Bromo-4-methylthiophene SDSbuy 2-Bromo-4-methylthiophene2-Bromo-4-methylthiophene supplier2-Bromo-4-methylthiophene uses2-Bromo-4-methylthiophene molecular weightprice of 2-Bromo-4-methylthiophene2-Bromo-4-methylthiophene chemical name formula of 2-Bromo-4-methylthiophene

Salutation:	*Country or Region:
*Applicant Name:	*Organization Name:
*Email Address:	Quantity:
CAS NO. :	Product Name:
Remarks:
Upload Pictures

CAS.No.		Product Name
Applicant Name *		Email Address *
Phone Number *		Organization Name*
Country or Region*		Quantity*
Remarks:

Product Name:
Cat. No.: .		CAS NO. :
Quantity:

2-Bromo-4-methylthiophene

CAS No. 53119-60-1

Recommended Products