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Structure of 53588-95-7
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tert-Butyl(2-cyanoethyl)carbamate serves as a robust, bench-stable protecting group for primary amines in synthetic workflows. The carbamate moiety enables selective N-alkylation and subsequent cleavage under mild acidic conditions. Its electron-deficient cyano group enhances reactivity in nucleophilic transformations, while the tert-butyl group provides steric shielding and ease of removal. This combination delivers precise control in peptide synthesis and complex molecule assembly.
tert-Butyl(2-cyanoethyl)carbamate serves as a robust, bench-stable protecting group for primary amines, enabling efficient incorporation of cyano functionality in peptide and small-molecule synthesis. It facilitates selective N-alkylation, undergoes mild acidolysis to release the free amine, and exhibits excellent compatibility with diverse reaction conditions. Its orthogonal cleavage profile supports sequential functionalization strategies in complex molecule assembly.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: