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Structure of 53590-47-9
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(5-Chloro-1H-indol-2-yl)methanol features a chlorinated indole core with a reactive primary alcohol at the 2-position, enabling direct functionalization in synthetic routes. This bench-stable, moisture-tolerant reagent integrates readily into bioactive molecule scaffolds and serves as a key intermediate for pharmaceutical and agrochemical development.
(5-Chloro-1H-indol-2-yl)methanol serves as a versatile building block in medicinal chemistry, enabling direct functionalization at the indole C2 position. Its benzylic alcohol functionality facilitates oxidation to aldehydes or carboxylic acids, and it participates reliably in coupling reactions with amines, thiols, and nucleophiles under standard conditions. The molecule exhibits good bench stability and is compatible with common protecting group strategies, supporting efficient synthesis of indole-based scaffolds for drug discovery.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H315-H319
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Precautionary Statements : P264-P280-P302+P352-P362
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Lot numbers can be found on the outside label of a product: