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Structure of 53595-65-6
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5-Bromothiophene-2-sulfonamide features a brominated thiophene core paired with a sulfonamide group, enabling direct incorporation into bioactive scaffolds. The electron-deficient thiophene ring enhances reactivity in cross-coupling processes, while the sulfonamide moiety provides hydrogen-bonding capacity and metabolic stability. This compound serves as a key building block for pharmaceutical intermediates and functional materials.
5-Bromothiophene-2-sulfonamide serves as a versatile building block in medicinal chemistry, enabling direct incorporation of both bromine and sulfonamide functionalities into target molecules. The bromine atom facilitates palladium-catalyzed cross-coupling reactions, while the sulfonamide group provides hydrogen bonding capacity and metabolic stability. Its bench-stable nature and compatibility with diverse reaction conditions make it a practical choice for constructing heterocyclic scaffolds and API intermediates.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P302+P352-P304+P340
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Lot numbers can be found on the outside label of a product: