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Structure of 537033-56-0
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4-Bromo-2,3,6-trifluorobenzaldehyde features a strategically positioned bromine atom and three fluorine substituents that collectively enhance electronic withdrawal and metabolic stability. This electron-deficient aromatic aldehyde integrates readily into cross-coupling reactions and serves as a key building block for pharmaceutical intermediates and functional materials.
4-Bromo-2,3,6-trifluorobenzaldehyde serves as a versatile building block in medicinal chemistry and materials science, enabling efficient construction of fluorinated heterocycles and pharmaceutical scaffolds. Its reactivity is well-documented in cross-coupling processes, including Suzuki-Miyaura and Buchwald-Hartwig reactions, facilitated by the orthogonal reactivity of the aldehyde and halogen functional groups. The molecule exhibits excellent bench stability and compatibility with standard purification methods, making it ideal for multi-step syntheses.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: