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CS-W001157 4
Total: USD 88.00

Tetrahydrofuran-2-ol

  • CAS No. 5371-52-8

  • Cat. No. CS-0197674
  • Molecule weight88.11
  • Purity≥95%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

Tetrahydrofuran-2-ol|CS-0197674

Structure of 5371-52-8

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General Information

  • CAS No. 5371-52-8
  • Cat. No. CS-0197674
  • Purity ≥95%
  • MDL No. None
  • Storage -20°C, sealed storage, away from moisture
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₄H₈O₂
  • Molecular Weight 88.11
  • Synonym(s) 2-Hydroxytetrahydrofuran
  • SMILES C1CC(O)OC1

Description

Tetrahydrofuran-2-ol delivers a chiral, hydroxylated scaffold ideal for asymmetric synthesis. This bench-stable, moisture-tolerant compound features a pendant alcohol that enables direct functionalization or derivatization. Its cyclic ether framework provides enhanced solubility and structural rigidity, streamlining incorporation into complex molecular architectures.

Synthesis

  • Route1
    • N-Ethylpropionamide|CS-0205055
      5129-72-6
    • ~92%
    • In-stock
      Tetrahydrofuran-2-ol|CS-0197674
      5371-52-8

    References

    • TEXACO DEVELOPMENT CORPORATION Patent: EP151515 B1, 1991 ;
  • Route2
    • null|null
      1191-99-7
    • ~67%
    • In-stock
      Tetrahydrofuran-2-ol|CS-0197674
      5371-52-8

    References

    • Kojima, Keisuke; Kimura, Masanari; Ueda, Satoshi; Tamaru, Yoshinao Tetrahedron, 2006 , vol. 62, # 32 p. 7512 - 7520
  • Route3
    • null|null
      201230-82-2
    • null|null
      107-18-6
    • ~%
    • In-stock
      Tetrahydrofuran-2-ol|CS-0197674
      5371-52-8
    • null|null
      38433-80-6

    References

    • Journal of the American Chemical Society, , vol. 125, # 22 p. 6608 - 6609

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS02
Signal Word : Danger
UN#: 1993
Class : 3
Packing Group : Ⅲ
Hazard Statements : H225
Precautionary Statements : P210-P233-P240-P241-P242-P243-P280-P370+P378-P501

Quality Control

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Computational Chemistry Data

  • TPSA   29.46
  • LogP   0.1152
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   0

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