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Structure of 53871-08-2
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tert-Butyl azetidine-3-carboxylate hydrochloride delivers a stable, moisture-tolerant scaffold for medicinal chemistry. The protected azetidine ring integrates readily into bioactive molecules, offering enhanced metabolic stability and favorable conformational control in peptide mimetics and kinase inhibitors.
tert-Butyl azetidine-3-carboxylate hydrochloride serves as a stable, bench-ready building block for the synthesis of azetidine-containing pharmaceuticals and bioactive molecules. Its protected amine functionality enables straightforward N-alkylation and palladium-catalyzed coupling reactions, while the strained azetidine ring facilitates nucleophilic displacement and cyclization processes. The tert-butyl ester group offers excellent stability and ease of removal under mild acidic conditions, making it ideal for iterative synthetic sequences in medicinal chemistry.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: