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Structure of 54-96-6
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Dansyl Chloride, also known as 5-dimethylamino naphthalene-1-sulfonyl chloride, is a pre-column derivatization reagent. After the derivatization reaction, the fluorescent derivatives are analyzed using several analytical methods like NMR, IR, UV-vis, and fluorescence microscopy. Dansyl Chloride is a typical aromatic sulphonyl chloride that reacts with various bases, resulting in derivatives with variable stability.Dansyl Chloride is used as a derivatization reagent to study extensive metabolism and low doses of ethinylestradiol administered during pre-clinical studies. Studies conducted to determine bisphenols in human serum through the HPLC method used Dansyl Chloride to obtain the derivative products. Dansyl Chloride derivatives are suitable for LC/MS determination and characterization of glyphosate, aminomethylphosphonic acid (AMPA), and glufosinate from food samples.
Amifampridine serves as a well-characterized potassium channel blocker with established utility in the synthesis of neuroactive compounds and ion channel modulators. Its pyridine-based scaffold enables robust functionalization and compatibility with standard coupling reactions, facilitating access to diverse heterocyclic architectures. The compound exhibits excellent bench stability and is amenable to purification via standard chromatographic methods, making it a reliable building block for medicinal chemistry campaigns targeting neuromuscular disorders.
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GHS Pictogram :
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GHS No : GHS06
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Signal Word : Danger
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UN#: 2811
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Class : 6.1
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Packing Group : Ⅱ
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Hazard Statements : H300+H330-H311-H319
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Precautionary Statements : P260-P264-P270-P271-P280-P284-P302+P352-P304+P340-P330-P361+P364-P405-P501
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Lot numbers can be found on the outside label of a product: