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CS-W001157 4
Total: USD 88.00

Amifampridine

  • CAS No. 54-96-6

  • Cat. No. CS-2778
  • Purity≥97%
  • MDL No.MFCD00006401
  • HazMat Fee +

    HazMat Fee

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

    The shipment is processed through FedEx Ground under the Limited Quantity option.

    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

Amifampridine|CS-2778

Structure of 54-96-6

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Description

Dansyl Chloride, also known as 5-dimethylamino naphthalene-1-sulfonyl chloride, is a pre-column derivatization reagent. After the derivatization reaction, the fluorescent derivatives are analyzed using several analytical methods like NMR, IR, UV-vis, and fluorescence microscopy. Dansyl Chloride is a typical aromatic sulphonyl chloride that reacts with various bases, resulting in derivatives with variable stability.Dansyl Chloride is used as a derivatization reagent to study extensive metabolism and low doses of ethinylestradiol administered during pre-clinical studies. Studies conducted to determine bisphenols in human serum through the HPLC method used Dansyl Chloride to obtain the derivative products. Dansyl Chloride derivatives are suitable for LC/MS determination and characterization of glyphosate, aminomethylphosphonic acid (AMPA), and glufosinate from food samples.

Application

Amifampridine serves as a well-characterized potassium channel blocker with established utility in the synthesis of neuroactive compounds and ion channel modulators. Its pyridine-based scaffold enables robust functionalization and compatibility with standard coupling reactions, facilitating access to diverse heterocyclic architectures. The compound exhibits excellent bench stability and is amenable to purification via standard chromatographic methods, making it a reliable building block for medicinal chemistry campaigns targeting neuromuscular disorders.

General Information

  • CAS No. 54-96-6
  • Cat. No. CS-2778
  • Purity ≥97%
  • MDL No. MFCD00006401
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₅H₇N₃
  • Molecular Weight None
  • Synonym(s) 3,4-Diaminopyridine
  • SMILES NC1=C(N)C=CN=C1

Computational Chemistry Data

  • TPSA   64.93
  • LogP   0.246
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   0

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS06
Signal Word : Danger
UN#: 2811
Class : 6.1
Packing Group : Ⅱ
Hazard Statements : H300+H330-H311-H319
Precautionary Statements : P260-P264-P270-P271-P280-P284-P302+P352-P304+P340-P330-P361+P364-P405-P501

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