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CS-W001157 4
Total: USD 88.00

4-Chloro-6,7-dihydro-5H-cyclopentapyrimidin-2-amine

  • CAS No. 5461-89-2

  • Cat. No. CS-0313990
  • Purity≥98%
  • MDL No.MFCD18916997

*For research and further manufacturing use only, not for direct human use.

4-Chloro-6,7-dihydro-5H-cyclopentapyrimidin-2-amine|CS-0313990

Structure of 5461-89-2

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General Information

  • CAS No. 5461-89-2
  • Cat. No. CS-0313990
  • Purity ≥98%
  • MDL No. MFCD18916997
  • Storage Sealed in dry,2-8℃
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₈ClN₃
  • Molecular Weight 169.61
  • Synonym(s) 4-Chloro-6,7-dihydro-5h-cyclopenta[d]pyrimidin-2-amine
  • SMILES NC1=NC(Cl)=C(CCC2)C2=N1

Synthesis

  • Route1
    • 2-amino-1,5,6,7-tetrahydrocyclopenta[d]pyrimidin-4-one|CS-0062085
      33081-06-0
    • ~76%
    • 4-Chloro-6,7-dihydro-5H-cyclopentapyrimidin-2-amine|CS-0313990
      5461-89-2

    References

    • Ohno; Mizukoshi; Komatsu; Kunoh; Nakamura; Katoh; Nagasaka Chemical and Pharmaceutical Bulletin, 1986 , vol. 34, # 10 p. 4150 - 4165
  • Route2

    References

    • Ross et al. Journal of the American Chemical Society, 1959 , vol. 81, p. 3108,3111
  • Route3

    References

    • Gangjee, Aleem; Zhao, Ying; Raghavan, Sudhir; Rohena, Cristina C.; Mooberry, Susan L.; Hamel, Ernest Journal of Medicinal Chemistry, 2013 , vol. 56, # 17 p. 6829 - 6844

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   51.8
  • LogP   1.2009
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   0

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