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Structure of 54660-78-5
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4-Chloropyrimidin-5-amine serves as a key heterocyclic building block in medicinal chemistry, featuring a chlorine substituent at the 4-position and an amine group at the 5-position. This combination enables direct coupling in cross-coupling reactions and facilitates rapid diversification of pyrimidine-based scaffolds. The compound exhibits good stability under standard conditions and integrates readily into kinase inhibitor and antiviral lead candidates.
4-Chloropyrimidin-5-amine serves as a versatile building block in medicinal chemistry, enabling efficient construction of pyrimidine-based scaffolds. Its reactive chloro group facilitates nucleophilic substitution with amines, thiols, and other heteroatoms, while the pendant amine supports further functionalization. The compound exhibits excellent bench stability and compatibility with standard coupling protocols, making it ideal for modular synthesis of kinase inhibitors and other bioactive heterocycles.
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GHS Pictogram :
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GHS No : GHS05,GHS07
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Signal Word : Danger
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UN#: 1759
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Class : 8
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Packing Group : Ⅲ
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Hazard Statements : H302-H318
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Precautionary Statements : P264-P270-P280-P330-P501
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Lot numbers can be found on the outside label of a product: