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Structure of 5470-49-5
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4-(Methylsulfonyl)aniline features a sulfonyl group that enhances solubility and metabolic stability, while the para-aniline functionality enables direct coupling in amide bond formation. This bench-stable derivative serves as a key intermediate in pharmaceutical synthesis and materials chemistry.
4-(Methylsulfonyl)aniline serves as a versatile building block in medicinal chemistry, enabling the introduction of a polar, metabolically stable sulfone group at the para position of an aromatic amine. Its bench-stable nature and compatibility with standard coupling reactions facilitate efficient synthesis of pharmaceutical intermediates and functionalized heterocycles. The molecule functions effectively as a precursor in amide formation, Suzuki-Miyaura coupling, and electrophilic substitution processes.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: