Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

5-Hydroxyphthalide

  • CAS No. 55104-35-3

  • Cat. No. CS-0028396
  • Purity≥95%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

5-Hydroxyphthalide|CS-0028396

Structure of 55104-35-3

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 55104-35-3
  • Cat. No. CS-0028396
  • Purity ≥95%
  • MDL No. None
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₆O₃
  • Molecular Weight 150.13
  • Synonym(s) NSC 28671
  • SMILES O=C1OCC2=C1C=CC(O)=C2

Description

5-Hydroxyphthalide serves as a key scaffold in synthetic organic chemistry, offering a versatile platform for derivatization. The hydroxyl group enables direct functionalization, while the lactone ring provides reactivity under mild conditions. This compound features high stability and solubility in common organic solvents, facilitating integration into complex molecular architectures.

Application

5-Hydroxyphthalide serves as a versatile building block in synthetic organic chemistry, enabling efficient access to substituted phthalides and related heterocycles. Its hydroxyl group facilitates derivatization via esterification, etherification, or metal-catalyzed coupling reactions, while the lactone functionality supports selective ring-opening transformations. The compound exhibits good bench stability and is compatible with common functional group manipulations, making it valuable for medicinal chemistry campaigns and natural product synthesis.

Synthesis

  • Route1

    References

    • Teixeira; Pereira; Da Silva; Guilardi; Paixao; Anconi; De Almeida; Ellena; Forlani Journal of Molecular Structure, 2014 , vol. 1061, # 1 p. 61 - 68
  • Route2
    • null|null
      134418-62-5
    • ~83%
    • In-stock
      5-Hydroxyphthalide|CS-0028396
      55104-35-3

    References

    • Padwa, Albert; Bullock, William H.; Norman, Bryan H.; Perumattam, John Journal of Organic Chemistry, 1991 , vol. 56, # 13 p. 4252 - 4259
  • Route3

    References

    • Levy; Stephen Journal of the Chemical Society, 1931 , p. 867,869 Full Text Show Details Tirouflet Bulletin de la Societe Scientifique de Bretagne, 1951 , vol. 26, p. Sonderheft 5, S. 7, 96 Comptes Rendus Hebdomadaires des Seances de l'Academie des Sciences, 1952 , vol. 235, p. 962

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   46.53
  • LogP   1.0626
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   0

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 5-Hydroxyphthalide sigma5-Hydroxyphthalide manufacturer5-Hydroxyphthalide price5-Hydroxyphthalide structure5-Hydroxyphthalide SDSbuy 5-Hydroxyphthalide5-Hydroxyphthalide supplier5-Hydroxyphthalide uses5-Hydroxyphthalide molecular weightprice of 5-Hydroxyphthalide5-Hydroxyphthalide chemical name formula of 5-Hydroxyphthalide
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label