2-Amino-5-methylpyrazine

Name: 2-Amino-5-methylpyrazine
Brand: ChemScene
Availability: InStock
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CAS No. 5521-58-4
Cat. No. CS-D0791
Purity≥97%
MDL No.MFCD08437664

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

Structure of 5521-58-4

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Description

2-Amino-5-methylpyrazine is a heterocyclic amine featuring a pyrazine core with strategically positioned amino and methyl groups. This combination imparts enhanced solubility and reactivity, enabling efficient incorporation into complex molecular architectures. The molecule exhibits bench-stable behavior under standard conditions, facilitating straightforward handling in synthetic workflows. Its electron-rich nature supports effective coordination in catalytic systems and metal-ligand assemblies.

Application

2-Amino-5-methylpyrazine serves as a versatile heterocyclic building block in medicinal chemistry and catalyst development. Its dual functionality—amine and methyl-substituted pyrazine ring—enables diverse coupling reactions, including palladium-catalyzed cross-couplings and electrophilic substitutions. The compound exhibits good bench stability and facilitates the construction of complex nitrogen-rich scaffolds relevant to pharmaceutical intermediates and ligand design.

General Information

CAS No. 5521-58-4
Cat. No. CS-D0791
Purity ≥97%
MDL No. MFCD08437664
Storage 4°C, protect from light
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₅H₇N₃
Molecular Weight 109.13
Synonym(s) None
SMILES NC1=NC=C(C)N=C1

Computational Chemistry Data

TPSA 51.8
LogP 0.36722
H_Acceptors 3
H_Donors 1
Rotatable_Bonds 0

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P260-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P337+P313-P362+P364-P403+P233-P405-P501

Quality Control

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Other Classifications

Bioactive Molecules Dye and Bio-assay Reagents

Building Blocks Functional Group Amine

Building Blocks Skeleton Aromatic heterocycle compounds Pyrazine compounds

Key Words

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2-Amino-5-methylpyrazine

CAS No. 5521-58-4

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