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Structure of 55243-02-2
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2,7-Dichloro-1,8-naphthyridine is a bench-stable, electron-deficient heterocycle featuring two chlorine substituents at key positions. This configuration enhances its reactivity in transition-metal-catalyzed couplings and enables efficient incorporation into pharmaceutical intermediates. The molecule’s planar structure supports π-stacking interactions, making it valuable in materials science applications.
2,7-Dichloro-1,8-naphthyridine serves as a versatile building block in medicinal chemistry and catalytic synthesis, enabling efficient functionalization at nitrogen-rich heterocyclic sites. Its dichloro substitution pattern facilitates palladium-catalyzed cross-coupling reactions and nucleophilic aromatic substitution, offering predictable regioselectivity. The compound exhibits excellent bench stability and compatibility with diverse reaction conditions, making it well-suited for constructing complex scaffolds in API development and materials science applications.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: