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CS-W001157 4
Total: USD 88.00

4-Amino-3-chloropyridin-2-ol

  • CAS No. 55290-73-8

  • Cat. No. CS-W004453
  • Purity≥98%
  • MDL No.MFCD09763693

*For research and further manufacturing use only, not for direct human use.

4-Amino-3-chloropyridin-2-ol|CS-W004453

Structure of 55290-73-8

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General Information

  • CAS No. 55290-73-8
  • Cat. No. CS-W004453
  • Purity ≥98%
  • MDL No. MFCD09763693
  • Storage 4°C, protect from light, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₅H₅ClN₂O
  • Molecular Weight 144.56
  • Synonym(s) 2-pyridinol, 4-amino-3-chloro-
  • SMILES ClC1=C(N)C=CN=C1O

Description

4-Amino-3-chloropyridin-2-ol features a pyridin-2-ol core with strategically positioned amino and chloro substituents, enabling precise electronic tuning. This bench-stable heterocycle integrates readily into medicinal chemistry scaffolds, offering enhanced solubility and hydrogen-bonding capacity for target-directed ligand design.

Application

4-Amino-3-chloropyridin-2-ol serves as a versatile building block in medicinal chemistry, enabling efficient access to substituted pyridine scaffolds. Its amino and hydroxyl groups offer orthogonal reactivity for coupling and derivatization, while the chloro substituent facilitates palladium-catalyzed cross-coupling reactions. The compound exhibits good bench stability and is compatible with standard purification methods, making it well-suited for iterative synthesis workflows in API development.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   59.14
  • LogP   1.0228
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   0

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