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CS-W001157 4
Total: USD 88.00

Aniline mustard

  • CAS No. 553-27-5

  • Cat. No. CS-0083103
  • Purity≥98%
  • MDL No.MFCD00013689
  • HazMat Fee +

    HazMat Fee

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

    The shipment is processed through FedEx Ground under the Limited Quantity option.

    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

Aniline mustard|CS-0083103

Structure of 553-27-5

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Description

Aniline mustard delivers a potent alkylating capability through its bis(2-chloroethyl)amine functionality, enabling efficient conjugation in bioconjugation workflows. The aniline group enhances solubility and modulates reactivity, offering improved handling over traditional mustard agents. This compound serves as a critical linker for site-specific protein modification and targeted drug delivery systems.

Application

Aniline mustard serves as a versatile bifunctional alkylating agent, enabling efficient synthesis of covalent inhibitors and DNA cross-linking agents. Its reactive mustard functionality facilitates site-specific modification under physiological conditions, while the aniline moiety enhances solubility and provides a handle for further derivatization. The compound exhibits sufficient bench stability for routine handling and is widely employed in medicinal chemistry workflows targeting nucleophilic biomolecules.

General Information

  • CAS No. 553-27-5
  • Cat. No. CS-0083103
  • Purity ≥98%
  • MDL No. MFCD00013689
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₁₃Cl₂N
  • Molecular Weight 218.12
  • Synonym(s) N,N-Bis(2-chloroethyl)aniline
  • SMILES ClCCN(C1=CC=CC=C1)CCCl

Computational Chemistry Data

  • TPSA   3.24
  • LogP   2.9706
  • H_Acceptors   1
  • H_Donors   0
  • Rotatable_Bonds   5

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS05
Signal Word : Danger
UN#: 1759
Class : 8
Packing Group : Ⅲ
Hazard Statements : H314
Precautionary Statements : P260-P264-P280-P301+P330+P331-P304+P340-P363-P405-P501

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