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CS-W001157 4
Total: USD 88.00

3-(Dimethylamino)-1-(3-pyridinyl)-2-propene-1-one

  • CAS No. 55314-16-4

  • Cat. No. CS-M1464
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

3-(Dimethylamino)-1-(3-pyridinyl)-2-propene-1-one|CS-M1464

Structure of 55314-16-4

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General Information

  • CAS No. 55314-16-4
  • Cat. No. CS-M1464
  • Purity ≥98%
  • MDL No. None
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₁₂N₂O
  • Molecular Weight 176.22
  • Synonym(s) 3-[3-(Dimethylamino)acryloyl]pyridine
  • SMILES O=C(/C=C/N(C)C)C1=CC=CN=C1

Description

Thapsigargin- induces down regulation of the EGF receptor is independent of protein kinase C activation. It is also used as an inducer of stored Ca2+ release.

Synthesis

  • Route1

    References

    • Son, Jong-Keun; Zhao, Long-Xuan; Basnet, Arjun; Thapa, Pritam; Karki, Radha; Na, Younghwa; Jahng, Yurngdong; Jeong, Tae Cheon; Jeong, Byeong-Seon; Lee, Chong-Soon; Lee, Eung-Seok European Journal of Medicinal Chemistry, 2008 , vol. 43, # 4 p. 675 - 682
  • Route2
    • 1-(Pyridin-3-yl)ethanone Imatinib Impurity|CS-0229620
      350-03-8
    • null|null
      68-12-2
    • ~82%
    • In-stock
      3-(Dimethylamino)-1-(3-pyridinyl)-2-propene-1-one|CS-M1464
      55314-16-4

    References

    • Arioli, Federica; Borrelli, Stella; Colombo, Francesco; Falchi, Federico; Filippi, Irene; Crespan, Emmanuele; Naldini, Antonella; Scalia, Giusy; Silvani, Alessandra; Maga, Giovanni; Carraro, Fabio; Botta, Maurizio; Passarella, Daniele ChemMedChem, 2011 , vol. 6, # 11 p. 2009 - 2018
  • Route3
    • 1-(Pyridin-3-yl)ethanone Imatinib Impurity|CS-0229620
      350-03-8
    • null|null
      5762-56-1
    • ~%
    • In-stock
      3-(Dimethylamino)-1-(3-pyridinyl)-2-propene-1-one|CS-M1464
      55314-16-4

    References

    • US4521422 A1, ;

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   33.2
  • LogP   1.3396
  • H_Acceptors   3
  • H_Donors   0
  • Rotatable_Bonds   3

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