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Structure of 55346-97-9
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4,5-Difluoro-2-nitrophenol delivers a dual electron-withdrawing motif through its para-nitro and adjacent difluoro substituents, enhancing reactivity in nucleophilic aromatic substitution. The fluorine atoms enable selective functionalization under mild conditions, while the nitro group serves as a potent handle for downstream transformations. This scaffold exhibits excellent stability under standard bench handling protocols.
4,5-Difluoro-2-nitrophenol serves as a versatile building block in medicinal chemistry and agrochemical synthesis, enabling direct introduction of fluorinated aryl motifs into complex heterocycles. Its reactivity profile facilitates nucleophilic aromatic substitution and transition-metal-catalyzed coupling reactions under standard conditions. The molecule exhibits good bench stability and is readily purified by recrystallization, supporting efficient integration into multi-step synthetic sequences.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H315-H319-H335
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Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P319-P332+P317-P337+P317-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: