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CS-W001157 4
Total: USD 88.00

4-Bromobenzimidamide hydrochloride

  • CAS No. 55368-42-8

  • Cat. No. CS-W002631
  • Molecule weight235.51
  • Purity≥97%
  • MDL No.MFCD00464967

*For research and further manufacturing use only, not for direct human use.

4-Bromobenzimidamide hydrochloride|CS-W002631

Structure of 55368-42-8

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General Information

  • CAS No. 55368-42-8
  • Cat. No. CS-W002631
  • Purity ≥97%
  • MDL No. MFCD00464967
  • Storage Store at room temperature, keep dry and cool
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₈BrClN₂
  • Molecular Weight 235.51
  • Synonym(s) amino(4-bromophenyl)methaniminium chloride
  • SMILES NC(=N)c1ccc(cc1)Br.Cl

Description

4-Bromobenzimidamide hydrochloride delivers a brominated benzimidamide scaffold with enhanced solubility and stability under standard conditions. This bench-stable reagent features a para-bromo substituent that enables efficient coupling reactions, facilitating the synthesis of bioactive heterocycles in medicinal chemistry workflows.

Application

4-Bromobenzimidamide hydrochloride serves as a versatile building block for the synthesis of biologically relevant benzimidazole scaffolds. Its bromine substituent enables palladium-catalyzed cross-coupling reactions, while the amidine functionality offers opportunities for derivatization and metal coordination. The hydrochloride salt enhances bench stability and solubility in polar solvents, facilitating handling and purification in standard synthetic workflows.

Synthesis

  • Route1

    References

    • Mahajan, Umesh S.; Godinde, Rupesh R.; Mandhare Synthetic Communications, 2011 , vol. 41, # 15 p. 2195 - 2199

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   49.87
  • LogP   2.15497
  • H_Acceptors   1
  • H_Donors   2
  • Rotatable_Bonds   1

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