(2S,3R,4S)-4-Hydroxyisoleucine

Name: (2S,3R,4S)-4-Hydroxyisoleucine
Brand: ChemScene
Availability: InStock
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CAS No. 55399-93-4
Cat. No. CS-W010987
Purity≥97%
MDL No.MFCD07357252

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

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*For research and further manufacturing use only, not for direct human use.

(2S,3R,4S)-4-Hydroxyisoleucine|CS-W010987

Structure of 55399-93-4

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Description

(2S,3R,4S)-4-Hydroxyisoleucine is a stereodefined hydroxylated amino acid featuring a unique tertiary alcohol at the C4 position. This configuration imparts enhanced metabolic stability and selective bioactivity, making it valuable for probing insulin-mimetic pathways in carbohydrate metabolism studies.

Application

(2S,3R,4S)-4-Hydroxyisoleucine serves as a valuable chiral building block for the synthesis of bioactive peptides and natural product analogs. Its well-defined stereochemistry enables predictable incorporation into peptide scaffolds, while the hydroxyl group provides a site for selective derivatization. The compound exhibits good bench stability and compatibility with standard coupling protocols, facilitating efficient access to complex targets in medicinal chemistry and synthetic biology applications.

General Information

CAS No. 55399-93-4
Cat. No. CS-W010987
Purity ≥97%
MDL No. MFCD07357252
Storage 4°C
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₆H₁₃NO₃
Molecular Weight 147.17
Synonym(s) (2S,3R,4S)-4-Hydroxy-L-isoleucine
SMILES O[C@@H](C)[C@H](C)[C@H](N)C(O)=O

Computational Chemistry Data

TPSA 83.55
LogP -0.5848
H_Acceptors 3
H_Donors 3
Rotatable_Bonds 3

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501

Quality Control

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Other Classifications

Bioactive Molecules Natural Products

Life Science Amino Acids and their Derivatives Isoleucine and derivatives

Chemical Biology Peptide Chemistry Amino Acid Derivatives

Key Words

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(2S,3R,4S)-4-Hydroxyisoleucine

CAS No. 55399-93-4

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