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CS-W001157 4
Total: USD 88.00

4-Hydroxyisoleucine

  • CAS No. 781658-23-9

  • Cat. No. CS-W016348
  • Purity≥98%
  • MDL No.MFCD06799350
  • HazMat Fee +

    HazMat Fee

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

    The shipment is processed through FedEx Ground under the Limited Quantity option.

    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

4-Hydroxyisoleucine|CS-W016348

Structure of 781658-23-9

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Description

Dehydroacetic acid is a pyrone derivative, that is typically synthesized by the base-catalyzed dimerization of diketene. It is used as a preservative in pharmaceutical, food and cosmetic products.Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.Dehydroacetic acid may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical, food and cosmetic formulations by chromatography.

Application

4-Hydroxyisoleucine serves as a valuable non-proteinogenic amino acid scaffold for medicinal chemistry and peptide-based drug discovery. Its hydroxylated side chain enhances hydrogen bonding capacity and metabolic stability, enabling improved solubility and target engagement in bioactive peptide sequences. The molecule exhibits bench stability and compatibility with standard solid-phase peptide synthesis protocols, facilitating efficient incorporation into complex molecular architectures.

General Information

  • CAS No. 781658-23-9
  • Cat. No. CS-W016348
  • Purity ≥98%
  • MDL No. MFCD06799350
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₁₃NO₃
  • Molecular Weight 147.17
  • Synonym(s) 4-​Hydroxy-​L-​isoleucine
  • SMILES N[C@@H]([C@@H](C)C(O)C)C(O)=O

Computational Chemistry Data

  • TPSA   83.55
  • LogP   -0.5848
  • H_Acceptors   3
  • H_Donors   3
  • Rotatable_Bonds   3

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501

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