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CS-W001157 4
Total: USD 88.00

Benzylhydrazine

  • CAS No. 555-96-4

  • Cat. No. CS-0013904
  • Molecule weight122.17
  • Purity≥95%
  • MDL No.MFCD00869518

*For research and further manufacturing use only, not for direct human use.

Benzylhydrazine|CS-0013904

Structure of 555-96-4

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General Information

  • CAS No. 555-96-4
  • Cat. No. CS-0013904
  • Purity ≥95%
  • MDL No. MFCD00869518
  • Storage -20°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₁₀N₂
  • Molecular Weight 122.17
  • Synonym(s) None
  • SMILES NNCC=1C=CC=CC1

Description

Benzylhydrazine serves as a key hydrazine derivative in synthetic organic chemistry, offering a reactive nitrogen functionality for constructing heterocycles and modifying carbonyl compounds. This bench-stable reagent integrates efficiently into multistep synthesis workflows, particularly in the formation of pyrazoles and related scaffolds.

Application

Benzylhydrazine serves as a reliable building block in heterocyclic synthesis, enabling efficient access to hydrazone and triazole scaffolds. Its benzyl-protected hydrazine functionality exhibits excellent bench stability and tolerates a range of reaction conditions, facilitating downstream functionalization. Widely employed in medicinal chemistry campaigns, it functions as a key intermediate for constructing bioactive nitrogen-containing frameworks with predictable reactivity.

Synthesis

  • Route1
    • null|null
      100-52-7
    • ~80%
    • In-stock
      Benzylhydrazine|CS-0013904
      555-96-4

    References

    • Malachowski, William P; Tie, Chenyang; Wang, Katherine; Broadrup, Robert L The Journal of organic chemistry, 2002 , vol. 67, # 25 p. 8962 - 8969
  • Route2

    References

    • Romanov-Michailidis, Fedor; Besnard, Celine; Alexakis, Alexandre Organic Letters, 2012 , vol. 14, # 18 p. 4906 - 4909,4 Title/Abstract Full Text Show Details Romanov-Michailidis, Fedor; Besnard, Celine; Alexakis, Alexandre Organic Letters, 2012 , vol. 14, # 18 p. 4906 - 4909
  • Route3

    References

    • US2006/223798 A1, ; Page/Page column 46 ; US 20060223798 A1

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS06
Signal Word : Danger
UN#: 2810
Class : 6.1
Packing Group : Ⅲ
Hazard Statements : H301-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362-P405-P501

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Computational Chemistry Data

  • TPSA   38.05
  • LogP   0.6499
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   2

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