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Structure of 55687-33-7
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2-Chloro-6-fluoroquinoxaline is a heterocyclic electrophile featuring orthogonal halogen handles enabling sequential cross-coupling. The electron-deficient core pairs with nucleophiles under palladium catalysis, while the fluorine atom facilitates further functionalization via nucleophilic aromatic substitution. This dual-reactive scaffold supports modular synthesis in medicinal chemistry and materials science.
2-Chloro-6-fluoroquinoxaline serves as a versatile building block in medicinal chemistry, enabling palladium-catalyzed cross-coupling reactions due to its complementary halogen reactivity. The ortho-chloro and meta-fluoro substituents provide orthogonal functionalization potential, facilitating sequential derivatization. Its stability under standard reaction conditions and compatibility with diverse nucleophiles make it well-suited for constructing complex heterocyclic scaffolds in API development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: