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CS-W001157 4
Total: USD 88.00

7-(3-Hydroxypropoxy)quinazolin-4-ol

  • CAS No. 557770-89-5

  • Cat. No. CS-0170828
  • Purity≥96%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

7-(3-Hydroxypropoxy)quinazolin-4-ol|CS-0170828

Structure of 557770-89-5

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General Information

  • CAS No. 557770-89-5
  • Cat. No. CS-0170828
  • Purity ≥96%
  • MDL No. None
  • Storage 4°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₁H₁₂N₂O₃
  • Molecular Weight 220.22
  • Synonym(s) 7-(3-Hydroxypropoxy)quinazolin-4(3H)-one
  • SMILES C(CO)COC1=CC2=NC=NC(=C2C=C1)O

Synthesis

  • Route1

    References

    • ASTRAZENECA AB; ASTRAZENECA UK LIMITED Patent: WO2004/105764 A1, 2004 ; Location in patent: Page 42 ; WO 2004/105764 A1
  • Route2

    References

    • WO2004/41829 A1, ; Page 92 ; WO 2004/041829 A1
  • Route3
    • 2-Amino-4-fluorobenzoic acid Afatinib Impurity|CS-0167288
      446-32-2
    • ~%
    • In-stock
      7-(3-Hydroxypropoxy)quinazolin-4-ol|CS-0170828
      557770-89-5

    References

    • Chemical Biology and Drug Design, , vol. 81, # 3 p. 399 - 407

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   75.47
  • LogP   1.0966
  • H_Acceptors   5
  • H_Donors   2
  • Rotatable_Bonds   4

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