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CS-W001157 4
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1-Pyridin-3-yl-ethylamine

  • CAS No. 56129-55-6

  • Cat. No. CS-D0742
  • Molecule weightNone
  • Purity≥98%
  • MDL No.MFCD01691641

*For research and further manufacturing use only, not for direct human use.

1-Pyridin-3-yl-ethylamine|CS-D0742

Structure of 56129-55-6

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General Information

  • CAS No. 56129-55-6
  • Cat. No. CS-D0742
  • Purity ≥98%
  • MDL No. MFCD01691641
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₁₀N₂
  • Molecular Weight None
  • Synonym(s) 5-22-09-00392 (Beilstein Handbook Reference)
  • SMILES NC(C)C1=CC=CN=C1

Description

1-Pyridin-3-yl-ethylamine features a pyridine ring linked to an ethylamine side chain, delivering a versatile scaffold for medicinal chemistry. This compound integrates readily into bioactive molecules due to its electron-rich aromatic core and amine functionality. The pendant amine enables conjugation or salt formation, enhancing solubility and enabling downstream derivatization. Its bench-stable nature supports reliable handling under standard conditions.

Application

1-Pyridin-3-yl-ethylamine serves as a versatile building block in medicinal chemistry, enabling the construction of bioactive heterocycles through standard coupling and functionalization reactions. Its pyridine moiety provides enhanced solubility and metabolic stability, while the primary amine facilitates straightforward derivatization. The compound exhibits good bench stability and is readily purified by distillation or column chromatography, making it well-suited for scalable synthesis workflows.

Synthesis

  • Route1
    • 1-(Pyridin-3-yl)ethanone Imatinib Impurity|CS-0229620
      350-03-8
    • ~58%
    • In-stock
      1-Pyridin-3-yl-ethylamine|CS-D0742
      56129-55-6

    References

    • WO2008/51493 A2, ; Page/Page column 105 ;
  • Route2
    • Methyl 3-pyridyl ketoxime|CS-W001846
      5973-83-1
    • ~%
    • In-stock
      1-Pyridin-3-yl-ethylamine|CS-D0742
      56129-55-6

    References

    • WO2003/99796 A1, ; Page 61 ; WO 03/099796 A1
  • Route3
    • (E)-1-(Pyridin-3-yl)ethanone oxime|CS-0369386
      106881-77-0
    • ~%
    • In-stock
      1-Pyridin-3-yl-ethylamine|CS-D0742
      56129-55-6

    References

    • Journal of the American Chemical Society, , vol. 66, p. 1293 Journal of the American Chemical Society, , vol. 63, p. 490

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS05,GHS06
Signal Word : Danger
UN#: 2810
Class : 6.1
Packing Group : Ⅲ
Hazard Statements : H301-H317-H318
Precautionary Statements : P261-P264-P270-P272-P280-P302+P352-P330-P362+P364-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   38.91
  • LogP   1.1013
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   1

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