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CS-W001157 4
Total: USD 88.00

4-Bromo-3-methoxybenzoic acid

  • CAS No. 56256-14-5

  • Cat. No. CS-D1614
  • Purity≥98%
  • MDL No.MFCD08436017
  • HazMat Fee +

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    The shipment is processed through FedEx Ground under the Limited Quantity option.

    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

4-Bromo-3-methoxybenzoic acid|CS-D1614

Structure of 56256-14-5

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Description

4-Bromo-3-methoxybenzoic acid features a bromine substituent at the para position relative to the carboxylic acid and a methoxy group ortho to the acid, delivering enhanced solubility and electronic tuning. This combination enables efficient coupling in cross-coupling reactions and facilitates incorporation into bioactive scaffolds requiring halogenated aromatic motifs.

Application

4-Bromo-3-methoxybenzoic acid serves as a versatile building block in medicinal chemistry and materials synthesis, enabling efficient access to functionalized aromatic scaffolds. Its well-defined reactivity profile supports direct coupling reactions, including Suzuki-Miyaura and Buchwald-Hartwig transformations, due to the orthogonal functionality of the bromo and methoxy groups. The carboxylic acid facilitates derivatization via amide formation or esterification, offering robust handles for further structural elaboration. Bench-stable and readily purified by recrystallization, it is optimized for use in standard synthetic workflows requiring predictable transformation outcomes.

General Information

  • CAS No. 56256-14-5
  • Cat. No. CS-D1614
  • Purity ≥98%
  • MDL No. MFCD08436017
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₇BrO₃
  • Molecular Weight 231.04
  • Synonym(s) 3-Methoxy-4-bromobenzoic acid; benzoic acid, 4-bromo-3-methoxy-
  • SMILES O=C(O)C1=CC=C(Br)C(OC)=C1

Computational Chemistry Data

  • TPSA   46.53
  • LogP   2.1559
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   2

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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