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Structure of 56256-14-5
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4-Bromo-3-methoxybenzoic acid features a bromine substituent at the para position relative to the carboxylic acid and a methoxy group ortho to the acid, delivering enhanced solubility and electronic tuning. This combination enables efficient coupling in cross-coupling reactions and facilitates incorporation into bioactive scaffolds requiring halogenated aromatic motifs.
4-Bromo-3-methoxybenzoic acid serves as a versatile building block in medicinal chemistry and materials synthesis, enabling efficient access to functionalized aromatic scaffolds. Its well-defined reactivity profile supports direct coupling reactions, including Suzuki-Miyaura and Buchwald-Hartwig transformations, due to the orthogonal functionality of the bromo and methoxy groups. The carboxylic acid facilitates derivatization via amide formation or esterification, offering robust handles for further structural elaboration. Bench-stable and readily purified by recrystallization, it is optimized for use in standard synthetic workflows requiring predictable transformation outcomes.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: