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CS-W001157 4
Total: USD 88.00

3-Amino-2-hydroxypropanoic acid

  • CAS No. 565-71-9

  • Cat. No. CS-W013682
  • Purity≥98%
  • MDL No.MFCD00008138

*For research and further manufacturing use only, not for direct human use.

3-Amino-2-hydroxypropanoic acid|CS-W013682

Structure of 565-71-9

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General Information

  • CAS No. 565-71-9
  • Cat. No. CS-W013682
  • Purity ≥98%
  • MDL No. MFCD00008138
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₃H₇NO₃
  • Molecular Weight 105.09
  • Synonym(s) None
  • SMILES NCC(O)C(O)=O

Description

3-Amino-2-hydroxypropanoic acid features a chiral center flanked by an amino group and a hydroxyl-bearing carbon, enabling its integration into peptide-like scaffolds. This structurally defined motif offers enhanced solubility and reactivity under standard conditions, supporting applications in synthetic biology and medicinal chemistry workflows.

Application

3-Amino-2-hydroxypropanoic acid serves as a key chiral building block for the synthesis of β-amino alcohols and peptidomimetics. Its well-defined stereochemistry and dual functional groups enable reliable coupling reactions and derivatization under standard conditions. The molecule exhibits good bench stability and facilitates straightforward purification, making it valuable in medicinal chemistry campaigns targeting bioactive scaffolds.

Synthesis

  • Route1
    • null|null
      74645-28-6
    • ~87%
    • In-stock
      3-Amino-2-hydroxypropanoic acid|CS-W013682
      565-71-9

    References

    • Yasohara, Yoshihiko; Hasegawa, Junzo Bioscience, Biotechnology and Biochemistry, 2001 , vol. 65, # 5 p. 1258 - 1260
  • Route2
    • (S)-Benzyl 2-oxooxazolidine-5-carboxylate|CS-0530033
      112663-80-6
    • ~93%
    • In-stock
      3-Amino-2-hydroxypropanoic acid|CS-W013682
      565-71-9

    References

    • Maeda; Suzuki; Sugano; Matsumoto Synthesis, 1988 , # 5 p. 401 - 402
  • Route3
    • (S)-3-(((benzyloxy)carbonyl)amino)-2-hydroxypropanoic acid|CS-0511029
      42491-79-2
    • ~%
    • In-stock
      3-Amino-2-hydroxypropanoic acid|CS-W013682
      565-71-9

    References

    • Carbohydrate research, , vol. 28, # 2 p. 263 - 280

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   83.55
  • LogP   -1.6094
  • H_Acceptors   3
  • H_Donors   3
  • Rotatable_Bonds   2

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