(R)-2-Phenylpyrrolidine

Name: (R)-2-Phenylpyrrolidine
Brand: ChemScene
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CAS No. 56523-47-8
Cat. No. CS-W006442
Molecule weightNone
Purity≥96%
MDL No.MFCD06762513

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

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General Information

CAS No. 56523-47-8
Cat. No. CS-W006442
Purity ≥96%
MDL No. MFCD06762513
Storage 4°C, protect from light
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₁₀H₁₃N
Molecular Weight None
Synonym(s) None
SMILES [C@@H]1(C2=CC=CC=C2)NCCC1

Description

(R)-2-Phenylpyrrolidine is a chiral building block featuring a stereodefined pyrrolidine ring fused to a phenyl group, offering high enantioselectivity in asymmetric synthesis. This bench-stable, moisture-tolerant scaffold integrates readily into medicinal chemistry campaigns targeting CNS-active compounds and catalytic ligands.

Application

(R)-2-Phenylpyrrolidine serves as a versatile chiral building block in medicinal chemistry, enabling the synthesis of bioactive heterocycles and pharmaceutical intermediates. Its stable, bench-ready nature and defined stereochemistry facilitate reliable incorporation into complex molecules. The compound reacts predictably with electrophiles and participates efficiently in C–H functionalization and coupling reactions, offering robust utility in asymmetric synthesis and API development workflows.

Safety Information

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GHS Pictogram :	GHS No : GHS05
Signal Word : Danger	UN#: 3265
Class : 8	Packing Group : Ⅲ
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

TPSA 12.03
LogP 2.1111
H_Acceptors 1
H_Donors 1
Rotatable_Bonds 1

Other Classifications

Building Blocks Skeleton Aromatic ring compounds Benzene compounds

Building Blocks Skeleton Chiral compounds Chiral Building Blocks

Key Words

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(R)-2-Phenylpyrrolidine

CAS No. 56523-47-8

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