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Structure of 56586-13-1
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2-Methylcyclohexanecarboxylic acid is a sterically hindered cycloaliphatic carboxylic acid featuring a methyl group at the C2 position. This substitution enhances rigidity and modulates reactivity, making it valuable in asymmetric synthesis and as a chiral auxiliary scaffold. The compound exhibits good stability under standard conditions and integrates readily into complex molecular architectures.
2-Methylcyclohexanecarboxylic acid serves as a versatile chiral building block in medicinal chemistry and natural product synthesis. Its cyclohexane core provides conformational rigidity, while the carboxylic acid functionality enables straightforward derivatization into amides, esters, and acyl chlorides. The adjacent methyl group enhances steric differentiation, improving selectivity in downstream transformations. Bench-stable and readily purified by recrystallization, it functions effectively in standard coupling reactions and heterocycle construction workflows.
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GHS Pictogram :
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GHS No : GHS05,GHS07
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Signal Word : Danger
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UN#: 3265
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Class : 8
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Packing Group : Ⅲ
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Hazard Statements : H227-H302-H318
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Precautionary Statements : P210-P264-P270-P280-P330-P370+P378-P501
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Lot numbers can be found on the outside label of a product: