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CS-W001157 4
Total: USD 88.00

6-(4-Formylphenyl)picolinic acid

  • CAS No. 566198-31-0

  • Cat. No. CS-0317623
  • Purity≥95%
  • MDL No.None
  • HazMat Fee +

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    The shipment is processed through FedEx Ground under the Limited Quantity option.

    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

6-(4-Formylphenyl)picolinic acid|CS-0317623

Structure of 566198-31-0

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Description

6-(4-Formylphenyl)picolinic acid features a conjugated aryl-aldehyde linked to a pyridine carboxylic acid scaffold, enabling direct integration into bioconjugation and metal coordination strategies. The para-formyl group provides a reactive handle for hydrazone or amine coupling, while the picolinic acid moiety offers strong chelation potential for transition metals. This bifunctional architecture supports modular synthesis in medicinal chemistry and materials design.

Application

6-(4-Formylphenyl)picolinic acid serves as a versatile bifunctional building block for medicinal chemistry and materials synthesis, combining a pyridine ring with an ortho-carboxylic acid and a para-formylphenyl group. The aldehyde functionality enables efficient imine formation, reductive amination, or Suzuki coupling, while the carboxylic acid supports amide bond construction or metal coordination. Its bench-stable nature and compatibility with standard functional group manipulations make it ideal for modular scaffold assembly in target-oriented synthesis.

General Information

  • CAS No. 566198-31-0
  • Cat. No. CS-0317623
  • Purity ≥95%
  • MDL No. None
  • Storage 4°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₃H₉NO₃
  • Molecular Weight 227.22
  • Synonym(s) 6-(4-Formylphenyl)-2-pyridinecarboxylic Acid
  • SMILES C1=CC(=NC(=C1)C(=O)O)C2=CC=C(C=C2)C=O

Computational Chemistry Data

  • TPSA   67.26
  • LogP   2.2593
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   3

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501

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