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Structure of 5685-05-2
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Thiazole-2(3H)-thione features a reactive thione tautomer stabilized by aromaticity, enabling direct participation in nucleophilic addition and metal coordination. This scaffold integrates readily into heterocyclic frameworks and serves as a key building block in medicinal chemistry and catalytic ligand design.
Thiazole-2(3H)-thione serves as a versatile heterocyclic building block in medicinal chemistry and synthetic organic chemistry. Its thione functionality enables reliable participation in nucleophilic additions, metal-catalyzed couplings, and electrophilic substitutions. The compound exhibits bench stability and facilitates the construction of complex thiazole-based scaffolds, including those found in bioactive molecules. Functional group tolerance and ease of purification support its utility in multi-step syntheses.
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GHS Pictogram :
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GHS No : GHS06
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Signal Word : Danger
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UN#: 2811
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Class : 6.1
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Packing Group : Ⅲ
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Hazard Statements : H301-H315-H319-H335
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Precautionary Statements : P264-P270-P330-P405-P501
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Lot numbers can be found on the outside label of a product: