Captopril EP Impurity D

Name: Captopril EP Impurity D
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 56970-78-6
Cat. No. CS-W016048
Purity≥95%
MDL No.MFCD01310530

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

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General Information

CAS No. 56970-78-6
Cat. No. CS-W016048
Purity ≥95%
MDL No. MFCD01310530
Storage 4°C
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₄H₇BrO₂
Molecular Weight 167.00
Synonym(s) 3-Bromoisobutyric acid
SMILES O=C(O)C(C)CBr

Description

Tween-20 is a polysorbate-based non-ionic surfactant. It is made up of three chemical units: aliphatic ester chains that hinder biomolecules from nonspecific interactions aliphatic chain that can be non-covalently adsorbed on a hydrophobic surfacehydrophilic terminal hydroxyl groups, which can be chemically modified for potential applications.Tween-20 can be used as a structure-directing agent in the preparation of mesoporous oxide films because of its ability to promote textural properties of the films such as controllable crystallinity, film morphology, tailor-designed pore structure, high BET surface area, and controlled film thickness. It is also used in the synthesis of AuNPs/TWEEN/GO composites, where Tween-20 acts as a reducing and immobilizing agent for AuNPs (Au nanoparticles) as well as a stabilizing agent for GO (graphene oxide).Tween-20 can also be used as an emulsifying, solubilizing, and wetting agent in a variety of liquid formulations.

Application

Captopril EP Impurity D serves as a well-characterized reference standard for the detection and quantification of a key impurity in captopril synthesis. It functions as a critical control in quality assurance workflows, enabling accurate assessment of batch consistency and degradation pathways. Its defined structure facilitates reliable HPLC method development and compliance with pharmacopeial specifications.

Synthesis

Route1
- 79-41-4
- ~92%
- In-stock
  
  56970-78-6
References
- Murakami; Hisaeda; Kohno; Ohno; Nishioka Bulletin of the Chemical Society of Japan, 1992 , vol. 65, # 11 p. 3094 - 3102
Route2
- 20609-71-6
- ~58%
- In-stock
  
  56970-78-6
References
- Salomon, Claudio J.; Mata, Ernesto G.; Mascaretti, Oreste A. Tetrahedron, 1993 , vol. 49, # 18 p. 3691 - 3734

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS05,GHS08
Signal Word : Danger	UN#: 3265
Class : 8	Packing Group : Ⅱ
Hazard Statements : H290-H302-H314-H332-H341
Precautionary Statements : P260-P264-P280-P301+P330+P331-P303+P361+P353-P304+P340-P305+P351+P338-P363-P405-P501

Quality Control

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Computational Chemistry Data

TPSA 37.3
LogP 1.102
H_Acceptors 1
H_Donors 1
Rotatable_Bonds 2

Other Classifications

Building Blocks Skeleton Fatty chain compounds

Building Blocks Functional Group Carboxylic Acid

Building Blocks Functional Group Bromide

Key Words

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Captopril EP Impurity D

CAS No. 56970-78-6

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