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Structure of 570407-10-2
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This thiazole derivative features a chlorothiophene moiety that enhances electron-withdrawing character and improves metabolic stability. The amine group enables facile coupling reactions, while the fused heterocyclic system provides rigidity and planarity, favoring π-stacking in target binding. Suitable for pharmaceutical intermediates requiring halogenated aromatic scaffolds with tunable reactivity.
4-(4-Chlorothiophen-2-yl)thiazol-2-amine serves as a versatile building block in medicinal chemistry, enabling the construction of heterocyclic scaffolds via cross-coupling and nucleophilic substitution reactions. Its thiazole core exhibits excellent bench stability and functional group tolerance, facilitating efficient derivatization for target-oriented synthesis. The 4-chlorothiophene moiety provides a reactive handle for Pd-catalyzed coupling, making this compound a practical intermediate in the development of bioactive molecules.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: