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Structure of 57184-25-5
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1-(Cyclopropylmethyl)piperazine is a sterically hindered piperazine derivative featuring a cyclopropylmethyl group that enhances lipophilicity and metabolic stability. This scaffold integrates readily into bioactive molecules, offering improved membrane permeability and solubility in medicinal chemistry applications.
1-(Cyclopropylmethyl)piperazine serves as a versatile nitrogen-containing building block in medicinal chemistry, enabling the construction of bioactive scaffolds through standard amine functionalization and coupling reactions. Its cyclopropylmethyl substituent enhances metabolic stability and modulates lipophilicity, while the piperazine core offers favorable solubility and hydrogen-bonding capacity. The compound exhibits excellent bench stability and compatibility with diverse reaction conditions, facilitating efficient synthesis of target molecules in multi-step routes.
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GHS Pictogram :
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GHS No : GHS05
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Signal Word : Danger
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UN#: 2735
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Class : 8
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Packing Group : Ⅲ
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Hazard Statements : H318
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Precautionary Statements : P280-P305+P351+P338-P310
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Lot numbers can be found on the outside label of a product: