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Structure of 59878-57-8
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Cyclopropyl(piperazin-1-yl)methanone features a rigid cyclopropyl group paired with a piperazinyl moiety, delivering enhanced metabolic stability and improved solubility. This structural combination enables efficient incorporation into bioactive molecules, particularly in kinase inhibitors and CNS-targeted compounds, where balanced lipophilicity and polarity are critical for permeability and target engagement.
Cyclopropyl(piperazin-1-yl)methanone serves as a versatile building block in medicinal chemistry, enabling the construction of bioactive heterocycles through standard amide coupling and reductive amination protocols. Its cyclopropyl-piperazine motif offers favorable metabolic stability and enhanced solubility, facilitating integration into drug-like scaffolds. The compound exhibits bench stability, ease of purification, and broad functional group tolerance, making it well-suited for iterative synthesis campaigns in API development.
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GHS No : GHS05,GHS07,GHS09
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Signal Word : Danger
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UN#: 3077
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Class : 9
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Packing Group : Ⅲ
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Hazard Statements : H302-H317-H318-H410
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Precautionary Statements : P261-P264-P270-P272-P273-P280-P302+P352-P391-P501
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Lot numbers can be found on the outside label of a product: