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CS-W001157 4
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3-Bromo-2-oxo-butyric acid ethyl ester

  • CAS No. 57332-84-0

  • Cat. No. CS-W006537
  • Purity≥95%
  • MDL No.None
  • HazMat Fee +

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    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

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*For research and further manufacturing use only, not for direct human use.

3-Bromo-2-oxo-butyric acid ethyl ester|CS-W006537

Structure of 57332-84-0

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Description

3-Bromo-2-oxo-butyric acid ethyl ester features a reactive β-keto ester scaffold paired with a bromine substituent at the α-position, enabling direct functionalization in synthetic sequences. This bench-stable reagent facilitates efficient C–C bond formation and serves as a key intermediate in the construction of complex heterocycles and bioactive molecules under mild conditions.

Application

3-Bromo-2-oxo-butyric acid ethyl ester serves as a versatile building block in synthetic organic chemistry, enabling efficient access to β-keto ester derivatives and functionalized heterocycles. Its bromine atom facilitates nucleophilic substitution and transition-metal-catalyzed coupling reactions, while the adjacent ketone and ester groups support enolization and aldol-type transformations. The compound exhibits good bench stability and is compatible with standard purification techniques, making it well-suited for iterative synthesis in medicinal chemistry and process development workflows.

General Information

  • CAS No. 57332-84-0
  • Cat. No. CS-W006537
  • Purity ≥95%
  • MDL No. None
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₉BrO₃
  • Molecular Weight 209.04
  • Synonym(s) Ethyl 3-bromo-2-oxobutanoate
  • SMILES CC(Br)C(C(OCC)=O)=O

Computational Chemistry Data

  • TPSA   43.37
  • LogP   0.902
  • H_Acceptors   3
  • H_Donors   0
  • Rotatable_Bonds   3

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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