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Structure of 57356-64-6
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5-Bromo-2-(piperidin-1-yl)pyrimidine features a bromine substituent at the C5 position and a piperidin-1-yl group at C2, creating a versatile scaffold for medicinal chemistry. The electron-rich pyrimidine core enables efficient coupling reactions, while the piperidinyl moiety enhances solubility and pharmacokinetic properties. This compound serves as a key building block in the synthesis of kinase inhibitors and other bioactive heterocycles.
5-Bromo-2-(piperidin-1-yl)pyrimidine serves as a versatile building block in medicinal chemistry, enabling efficient construction of pyrimidine-based scaffolds through palladium-catalyzed cross-coupling reactions. The bromine at the 5-position provides high reactivity in Suzuki, Stille, and Negishi couplings, while the piperidinyl group enhances solubility and offers a handle for further functionalization. Bench-stable and readily purified, it functions reliably in multi-step syntheses targeting kinase inhibitors and other bioactive heterocycles.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: