Lot numbers can be found on the outside label of a product:
Benzoic acid, 6-amino-3-bromo-2-methyl-, methyl ester
-
CAS No. 573692-58-7
- Cat. No. CS-0030467
- Purity≥96%
- MDL No.MFCD16036438
*For research and further manufacturing use only, not for direct human use.
Structure of 573692-58-7
Please choose your location and provide accurate information for you
| Size |
|
Price | Quantity | |||
|---|---|---|---|---|---|---|
|
* Please select Quantity before adding items. |
||||||
Recommended Products
General Information
- CAS No. 573692-58-7
- Cat. No. CS-0030467
- Purity ≥96%
- MDL No. MFCD16036438
- Storage 4°C, protect from light
- Shipping Room temperature in continental US; may vary elsewhere.
- Molecular Formula C₉H₁₀BrNO₂
- Molecular Weight 244.09
- Synonym(s) None
- SMILES O=C(OC)C1=C(N)C=CC(Br)=C1C
Description
Methyl 6-amino-3-bromo-2-methylbenzoate features a brominated aromatic core with complementary amino and ester functionalities, enabling direct incorporation into Suzuki-Miyaura cross-coupling and amide derivatization workflows. The para-amino group enhances electron density for reactive coupling, while the methyl substituent provides steric control. This bench-stable reagent supports efficient synthesis of functionalized heterocycles and bioactive scaffolds under standard conditions.
Application
Methyl 6-amino-3-bromo-2-methylbenzoate serves as a versatile building block in medicinal chemistry and agrochemical synthesis, enabling palladium-catalyzed cross-coupling reactions due to its ortho-bromo and meta-amino functionalization. The methyl ester group provides a handle for selective derivatization, while the amino and bromo substituents offer orthogonal reactivity. Bench-stable and compatible with standard purification methods, it facilitates efficient access to substituted heterocycles and complex scaffolds in multi-step syntheses.
Synthesis
-
Route1
-
In-stock
99548-54-6 - ~%
-
In-stock
573692-58-7
References
-
ABBOTT LABORATORIES Patent: WO2004/108672 A1, 2004 ; Location in patent: Page 52; 53 ; WO 2004/108672 A1
-
-
Route2
-
894351-65-6 - ~%
-
In-stock
573692-58-7
References
-
Curtin, Michael L.; Davidsen, Steven K.; Frey, Robin R.; Heyman, Howard R.; Holms, James H.; Michaelides, Michael; Steinman, Douglas H. Patent: US2005/26976 A1, 2005 ; Location in patent: Page/Page column 24 ; US 20050026976 A1
-
-
Route3
-
In-stock
![5-Methyl-2H-benzo[d][1,3]oxazine-2,4(1H)-dione|CS-0226753](https://file.chemscene.com/productPIC/CS-0226753.gif)
20877-81-0 - ~%
-
In-stock
573692-58-7
References
-
Wang, Gary T.; Mantei, Robert A.; Kawai, Megumi; Tedrow, Jason S.; Barnes, David M.; Wang, Jieyi; Zhang, Qian; Lou, Pingping; Garcia, Lora A.; Bouska, Jennifer; Yates, Melinda; Park, Chang; Judge, Russell A.; Lesniewski, Richard; Sheppard, George S.; Bell, Randy L. Bioorganic and Medicinal Chemistry Letters, 2007 , vol. 17, # 10 p. 2817 - 2822
-
Safety Information
Download SDS|
GHS Pictogram :
|
GHS No : GHS07
|
|
Signal Word : Warning
|
UN#: N/A
|
|
Class : N/A
|
Packing Group : N/A
|
|
Hazard Statements : H302-H315-H319-H335
|
|
|
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
|
|
Quality Control
Computational Chemistry Data
- TPSA 52.32
- LogP 2.12632
- H_Acceptors 3
- H_Donors 1
- Rotatable_Bonds 1
Similar Products
Other Classifications
Recently Viewed Products
Leave US a Message
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Upload Pictures
|
|
Key Words
- 573692-58-7 sigma573692-58-7 manufacturer573692-58-7 price573692-58-7 structure573692-58-7 SDSbuy 573692-58-7573692-58-7 supplier573692-58-7 uses573692-58-7 molecular weightprice of 573692-58-7573692-58-7 chemical name formula of 573692-58-7