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CS-W001157 4
Total: USD 88.00

1-Fluoro-2-naphthoic acid

  • CAS No. 574-97-0

  • Cat. No. CS-0453855
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

1-Fluoro-2-naphthoic acid|CS-0453855

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General Information

  • CAS No. 574-97-0
  • Cat. No. CS-0453855
  • Purity ≥98%
  • MDL No. None
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₁H₇FO₂
  • Molecular Weight 190.17
  • Synonym(s) 1-Fluoronaphthalene-2-carboxylic acid
  • SMILES C1=CC=C2C(=C1)C=CC(=C2F)C(=O)O

Description

1-Fluoro-2-naphthoic acid features a fluorine atom at the 1-position of the naphthalene ring, enhancing electron-withdrawal and directing electrophilic substitution. This bench-stable carboxylic acid integrates readily into synthetic routes requiring polarized aromatic systems, serving as a key intermediate in pharmaceutical and agrochemical development.

Application

1-Fluoro-2-naphthoic acid serves as a versatile building block for the synthesis of fluorinated naphthalene derivatives, enabling direct introduction of both a carboxylic acid and a fluoro substituent at adjacent positions. Its bench-stable nature and compatibility with standard coupling reactions facilitate efficient functionalization in medicinal chemistry and materials science applications.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   37.3
  • LogP   2.6771
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   1

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