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CS-W001157 4
Total: USD 88.00

Ethyl 2-amidinoacetate hydrochloride

  • CAS No. 57508-48-2

  • Cat. No. CS-W003345
  • Molecule weight166.61
  • Purity≥95%
  • MDL No.MFCD06797615

*For research and further manufacturing use only, not for direct human use.

Ethyl 2-amidinoacetate hydrochloride|CS-W003345

Structure of 57508-48-2

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General Information

  • CAS No. 57508-48-2
  • Cat. No. CS-W003345
  • Purity ≥95%
  • MDL No. MFCD06797615
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₅H₁₁ClN₂O₂
  • Molecular Weight 166.61
  • Synonym(s) Propanoic acid, 3-amino-3-imino-, ethyl ester
  • SMILES CCOC(=O)CC(=N)N.Cl

Description

Ethyl 2-amidinoacetate hydrochloride delivers a stable, moisture-tolerant platform for amidine synthesis. This bench-stable salt integrates a reactive amidino group flanked by an ester functionality, enabling direct coupling in peptide-like scaffolds or transition-metal-catalyzed transformations under standard conditions.

Application

Ethyl 2-amidinoacetate hydrochloride serves as a versatile building block for amidine and guanidine-containing heterocycles, enabling efficient access to bioactive scaffolds. Its stable crystalline form facilitates handling and purification, while the protected amidino group exhibits predictable reactivity in condensation and cyclization reactions. The compound functions as a key intermediate in the synthesis of nitrogen-rich pharmaceuticals and agrochemicals, particularly in routes involving amide bond formation or ring closure under mild conditions.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   76.17
  • LogP   0.29737
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   3

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