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CS-W001157 4
Total: USD 88.00

1-(3-Chloropropyl)pyrrolidine hydrochloride

  • CAS No. 57616-69-0

  • Cat. No. CS-0054075
  • Purity≥97%
  • MDL No.MFCD07787233

*For research and further manufacturing use only, not for direct human use.

1-(3-Chloropropyl)pyrrolidine hydrochloride|CS-0054075

Structure of 57616-69-0

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General Information

  • CAS No. 57616-69-0
  • Cat. No. CS-0054075
  • Purity ≥97%
  • MDL No. MFCD07787233
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₁₅Cl₂N
  • Molecular Weight 184.11
  • Synonym(s) N-(3-Chloropropyl)pyrrolidine Hydrochloride
  • SMILES ClCCCN1CCCC1.Cl

Description

1-(3-Chloropropyl)pyrrolidine hydrochloride features a pyrrolidine ring linked to a chloropropyl chain, delivering a reactive electrophilic handle for conjugation. This bench-stable salt form enhances solubility and handling in aqueous or polar organic media. The chloride group enables efficient nucleophilic substitution reactions, making it ideal for synthesizing functionalized polymers, bioconjugates, and targeted probes.

Application

1-(3-Chloropropyl)pyrrolidine hydrochloride serves as a versatile bifunctional building block, enabling efficient synthesis of pyrrolidine-containing scaffolds. The chloroalkyl side chain facilitates nucleophilic substitution reactions, while the protonated pyrrolidine nitrogen enhances solubility and reactivity in polar media. Its bench-stable crystalline form simplifies handling and purification, making it ideal for modular library construction and medicinal chemistry applications requiring controlled functionalization.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   3.24
  • LogP   2.1329
  • H_Acceptors   1
  • H_Donors   0
  • Rotatable_Bonds   3

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