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CS-W001157 4
Total: USD 88.00

Spiro[2.4]heptan-4-one

  • CAS No. 5771-32-4

  • Cat. No. CS-0139731
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

Spiro[2.4]heptan-4-one|CS-0139731

Structure of 5771-32-4

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General Information

  • CAS No. 5771-32-4
  • Cat. No. CS-0139731
  • Purity ≥97%
  • MDL No. None
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₁₀O
  • Molecular Weight 110.15
  • Synonym(s) spiro[2.4]heptan-7-one
  • SMILES O=C(CCC1)C21CC2

Description

Spiro[2.4]heptan-4-one features a rigid, three-dimensional spirocyclic core that imparts exceptional conformational stability. This bicyclic ketone integrates seamlessly into complex molecular architectures, serving as a key scaffold in synthetic routes to bioactive compounds and functional materials.

Application

Spiro[2.4]heptan-4-one serves as a rigid, bicyclic scaffold enabling access to diverse heterocyclic systems and natural product analogs. Its ketone functionality facilitates nucleophilic addition, enolization, and metal-catalyzed transformations, while the spirocyclic core imparts conformational stability and enhanced metabolic resistance. The compound exhibits excellent bench stability and compatibility with standard synthetic protocols, making it a practical building block for medicinal chemistry and process development.

Synthesis

  • Route1
    • null|null
      75-21-8
    • null|null
      15090-41-2
    • ~40%
    • In-stock
      Spiro[2.4]heptan-4-one|CS-0139731
      5771-32-4

    References

    • Jacks, Thomas E.; Nibbe, Heidi; Wiemer, David F. Journal of Organic Chemistry, 1993 , vol. 58, # 17 p. 4584 - 4588
  • Route2
    • null|null
      56475-46-8
    • ~%
    • In-stock
      Spiro[2.4]heptan-4-one|CS-0139731
      5771-32-4

    References

    • Larcheveque,M. et al. Journal of Organometallic Chemistry, 1975 , vol. 87, p. 25 - 31
  • Route3
    • null|null
      1191-95-3
    • null|null
      10575-90-3
    • ~81%
    • In-stock
      Spiro[2.4]heptan-4-one|CS-0139731
      5771-32-4
    • null|null
      5743-83-9
    • In-stock
      Spiro[3.3]heptan-1-one|CS-0054569
      63049-05-8
    • null|null
      81479-05-2

    References

    • Fitjer, Lutz; Wehle, Detlef Chemische Berichte, 1982 , vol. 115, # 3 p. 1061 - 1069

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS02
Signal Word : Danger
UN#: 1993
Class : 3
Packing Group : Ⅲ
Hazard Statements : H225
Precautionary Statements : P210-P243-P273-P403

Quality Control

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Computational Chemistry Data

  • TPSA   17.07
  • LogP   1.5196
  • H_Acceptors   1
  • H_Donors   0
  • Rotatable_Bonds   0

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