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Structure of 577778-58-6
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Topiroxostat is a potent, selective inhibitor of xanthine oxidase, designed to reduce uric acid production in hyperuricemic conditions. This small molecule features a unique pyrazolo[1,5-a]pyrimidine core that enables tight binding to the enzyme's active site. It exhibits favorable metabolic stability and oral bioavailability, making it suitable for chronic dosing regimens. The compound demonstrates efficacy in lowering serum uric acid levels under standard conditions.
Topiroxostat serves as a potent, selective inhibitor of xanthine oxidase, enabling precise modulation of uric acid biosynthesis. Its well-defined structure facilitates reliable use in metabolic studies and preclinical research. The compound exhibits favorable bench stability and compatibility with standard assay workflows, supporting consistent performance in enzymatic inhibition profiling and pharmacodynamic evaluation.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: