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CS-W001157 4
Total: USD 88.00

2,3-Dihydrobenzofuran-6-amine

  • CAS No. 57786-34-2

  • Cat. No. CS-0119925
  • Molecule weight135.16
  • Purity≥97%
  • MDL No.MFCD16658151

*For research and further manufacturing use only, not for direct human use.

2,3-Dihydrobenzofuran-6-amine|CS-0119925

Structure of 57786-34-2

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General Information

  • CAS No. 57786-34-2
  • Cat. No. CS-0119925
  • Purity ≥97%
  • MDL No. MFCD16658151
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₉NO
  • Molecular Weight 135.16
  • Synonym(s) 2,3-dihydro-1-benzofuranyl-6-amine
  • SMILES NC1=CC=C2CCOC2=C1

Description

2,3-Dihydrobenzofuran-6-amine delivers a rigid, electron-rich heterocyclic scaffold ideal for medicinal chemistry applications. This bench-stable amine features a fused bicyclic core with a pendant primary amine, enabling direct incorporation into diverse molecular architectures via amidation or coupling reactions. The oxygen-containing ring system enhances solubility and modulates electronic properties.

Application

2,3-Dihydrobenzofuran-6-amine serves as a versatile building block in medicinal chemistry, enabling efficient access to bioactive heterocycles. Its electron-rich aromatic core and primary amine functionality facilitate straightforward derivatization via amidation, alkylation, and transition-metal-catalyzed coupling reactions. The compound exhibits good bench stability and is readily purified by standard chromatographic methods, making it well-suited for iterative synthesis campaigns targeting CNS-directed therapeutics and kinase inhibitors.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   35.25
  • LogP   1.2037
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   0

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