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CS-W001157 4
Total: USD 88.00

5-Hydroxyquinoline

  • CAS No. 578-67-6

  • Cat. No. CS-W008754
  • Purity≥97%
  • MDL No.MFCD00006792

*For research and further manufacturing use only, not for direct human use.

5-Hydroxyquinoline|CS-W008754

Structure of 578-67-6

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General Information

  • CAS No. 578-67-6
  • Cat. No. CS-W008754
  • Purity ≥97%
  • MDL No. MFCD00006792
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₇NO
  • Molecular Weight 145.16
  • Synonym(s) Quinolin-5(1H)-one
  • SMILES OC1=C2C(N=CC=C2)=CC=C1

Description

2?-Deoxycytidine (deoxyC) is one of the deoxynucleosides which after phosphorylation to dCTP is used to synthesis DNA via various DNA polymerases or reverse transcriptases. 2?-Deoxycytidine (deoxyC) is the substrate for deoxycytidine deaminase (EC 3.5.4.14) which converts it into 2?-deoxyuridine. 2?-Deoxycytidine is phosphorylated to the nucleotide dCMP by the enzyme deoxycytidine kinase (DCK).

Synthesis

  • Route1

    References

    • VIAMET PHARMACEUTICALS, INC. Patent: US2012/329802 A1, 2012 ; Location in patent: Page/Page column 25-26 ;
  • Route2
    • Quinolin-5-yl trifluoromethanesulfonate|CS-0902098
      177734-78-0
    • ~98%
    • In-stock
      5-Hydroxyquinoline|CS-W008754
      578-67-6

    References

    • Ohgiya, Tadaaki; Nishiyama, Shigeru Tetrahedron Letters, 2004 , vol. 45, # 33 p. 6317 - 6320
  • Route3

    References

    • Li, Jianke; Kung, Daniel W.; Griffith, David A. Tetrahedron Letters, 2010 , vol. 51, # 30 p. 3876 - 3878

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   33.12
  • LogP   1.9404
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   0

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