H-Lys(Z)-NH2.HCl

Name: H-Lys(Z)-NH2.HCl
Brand: ChemScene
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CAS No. 58117-53-6
Cat. No. CS-0149999
Purity≥97%
MDL No.MFCD00035520

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

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Structure of 58117-53-6

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Description

H-Lys(Z)-NH2·HCl features a protected lysine side chain with a benzyloxycarbonyl (Z) group, enabling selective incorporation in peptide synthesis. The protonated amine ensures solubility and stability under standard reaction conditions. This derivative facilitates efficient coupling steps while minimizing side reactions.

Application

H-Lys(Z)-NH₂·HCl serves as a protected lysine building block for peptide synthesis, enabling selective incorporation of the ε-amino group in solid-phase and solution-phase workflows. The benzyloxycarbonyl (Z) group provides robust protection under standard conditions, while the terminal amine is delivered as a stable hydrochloride salt, facilitating handling and purification. Its compatibility with diverse coupling reagents and orthogonal deprotection strategies supports efficient access to complex peptide architectures.

General Information

CAS No. 58117-53-6
Cat. No. CS-0149999
Purity ≥97%
MDL No. MFCD00035520
Storage Store at room temperature, keep dry and cool
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₁₄H₂₂ClN₃O₃
Molecular Weight 315.80
Synonym(s) Benzyl (S)-(5,6-diamino-6-oxohexyl)carbamate monohydrochloride
SMILES NC([C@@H](N)CCCCNC(OCC1=CC=CC=C1)=O)=O.Cl

Computational Chemistry Data

TPSA 107.44
LogP 1.3175
H_Acceptors 4
H_Donors 3
Rotatable_Bonds 8

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501

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Other Classifications

Building Blocks Functional Group Amide

Building Blocks Functional Group Ester

Building Blocks Skeleton Aromatic ring compounds Benzene compounds

Building Blocks Skeleton Chiral compounds Chiral Building Blocks

Key Words

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H-Lys(Z)-NH2.HCl

CAS No. 58117-53-6

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