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Structure of 58123-72-1
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3-Chloro-4-iodobenzoic acid features a benzene ring bearing chlorine and iodine substituents at ortho and meta positions relative to the carboxylic acid group. This configuration imparts enhanced electrophilicity and stability, enabling efficient coupling reactions in cross-coupling protocols. The carboxylic acid functionality facilitates direct derivatization or salt formation for improved solubility and handling.
3-Chloro-4-iodobenzoic acid serves as a versatile building block for transition-metal-catalyzed cross-coupling reactions, enabling efficient construction of biaryl and heteroaryl scaffolds. The ortho-chloro and para-iodo substituents offer orthogonal reactivity for sequential functionalization. Its bench-stable carboxylic acid group facilitates direct derivatization or use in amide coupling protocols, making it well-suited for medicinal chemistry and process development workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: