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CS-W001157 4
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(4-(Ethylsulfonyl)phenyl)methanamine

  • CAS No. 583837-94-9

  • Cat. No. CS-0054352
  • Purity≥97%
  • MDL No.MFCD10032480

*For research and further manufacturing use only, not for direct human use.

(4-(Ethylsulfonyl)phenyl)methanamine|CS-0054352

Structure of 583837-94-9

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General Information

  • CAS No. 583837-94-9
  • Cat. No. CS-0054352
  • Purity ≥97%
  • MDL No. MFCD10032480
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₁₃NO₂S
  • Molecular Weight 199.27
  • Synonym(s) [4-(Ethanesulphonyl)phenyl]methanamine
  • SMILES NCC1=CC=C(S(=O)(CC)=O)C=C1

Description

This bench-stable amine features a para-ethysulfonyl aryl group that enhances solubility and metabolic stability. The primary amine functionality enables direct coupling in amide bond formation, streamlining access to functionalized biaryl scaffolds for medicinal chemistry applications.

Application

(4-(Ethylsulfonyl)phenyl)methanamine serves as a versatile building block in medicinal chemistry, enabling the synthesis of sulfonamide-containing pharmaceutical intermediates. Its ethylsulfonyl group provides enhanced metabolic stability and modulates solubility, while the primary amine facilitates straightforward derivatization via acylation, alkylation, or coupling reactions. The compound exhibits excellent bench stability and is readily purified by standard chromatographic methods, making it well-suited for scalable synthesis workflows.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   60.16
  • LogP   0.9389
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   3

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