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Structure of 58401-43-7
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4-Chloroquinolin-3-amine is a heterocyclic amine featuring a chlorine substituent at the 4-position of the quinoline core. This electron-deficient scaffold integrates readily into pharmaceutical intermediates and functional materials, offering enhanced reactivity in cross-coupling transformations. The pendant amino group enables further derivatization, while the planar aromatic system supports π-stacking interactions in supramolecular systems.
4-Chloroquinolin-3-amine serves as a versatile building block in medicinal chemistry, enabling direct functionalization at the 3-position via palladium-catalyzed cross-coupling reactions. Its chlorine atom facilitates efficient derivatization under mild conditions, while the amine group provides a handle for conjugation or salt formation. The scaffold exhibits excellent bench stability and compatibility with diverse reaction environments, making it well-suited for iterative synthesis of quinoline-based pharmaceutical candidates.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: